Table 1

MICs of various β-lactams for E. coli strain IMOTU11 and E. coli strains transformed with NDM-1 or NDM-8

AntibioticMIC (μg/ml)
IOMTU11pHSG398/NDM-8pHSG398/NDM-1pHSG398
Ampicillin>1,0242562564
Ampicillin-sulbactam>1,0241281282
Aztreonam>1,0240.030.030.03
Cefepime1,0240.50.5<0.25
CefmetazoleNDa421
CefoselisND84<0.25
Cefotaxime>1,02488<0.25
Cefoxitin>1,02464648
CefozopranND88<0.25
CefpiromeND21<0.25
CefsulodinND>512>512256
Ceftazidime>1,024256256<0.25
CeftriaxoneND1632<0.25
CefuroximeND5125124
Cephradine>1,02451225616
DoripenemND0.1250.060.03
Imipenem2560.50.250.06
Meropenem2560.250.50.03
MoxalactamND168<0.25
PanipenemND0.50.250.06
Penicillin G>1,02425625632
Piperacillin>1,02416162
Piperacillin-tazobactam>1,024881
Ticarcillin>1,024>512>5122
Ticarcillin-clavulanic acid5125125124
  • a ND, not determined.