Table 1

MIC determination by use of MIC test strips and the microdilution method

StrainTime point (h)MethodMIC (mg/liter)a
Amphotericin BVoriconazolePosaconazoleAnidulafunginCaspofungin
Wild type24Test strip0.125–0.190.064–0.0940.047–0.0640.004–0.006*0.032*
48Test strip1.50.0940.0940.006–0.008**0.032–0.047**
2/7/124Test strip0.094–0.1250.064–0.0940.032–0.0470.004–0.006*0.032–0.047*
48Test strip1.0–1.50.0940.0940.006–0.008**0.047–0.064**
Wild type48Microdilution10.25ND<0.032***ND
2/7/148Microdilution10.25ND<0.032***ND
  • a *, microcolonies were present in the inhibition zone; **, difficult to evaluate due to microcolonies; ***, data are MECs (at the lowest concentration tested, a hyperbranching phenotype of colonies was observed); ND, not determined.