TABLE 3

Drug resistance levels of the 57 selected clinical isolates

AntibioticResistance levels of clinical isolatesReference strain MICs (μg/ml)
MIC range (μg/ml)% in resistance categoryaMIC50/MIC90PAO1CMZ091PAOW1PAOW2
SIR
Tobramycin0.5–12891091/40.5121
Amikacin4–648414216/3248168
Apramycin16–256NDNDND64/12816326464
Ciprofloxacin0.125–64675280.5/320.250.50.50.5
Cefepime2–325330178/3248168
Ceftazidime0.5–3295322/82222
Ticarcillin4 to >1,0244251732/6416161616
  • a According to the current CLSI breakpoints for tobramycin (S, ≤4 μg/ml; R, ≥16 μg/ml), amikacin (S, ≤16 μg/ml; R, ≥64 μg/ml), ciprofloxacin (S, ≤1 μg/ml; R, ≥4 μg/ml), cefepime (S, ≤8 μg/ml; R, ≥32 μg/ml), ceftazidime (S, ≤8 μg/ml; R, ≥32 μg/ml), ticarcillin (S, ≤16 μg/ml; R, ≥128 μg/ml). I, intermediate; ND, not defined.