TABLE 1

Hematological profile for guinea pigs after chronic treatment with GRFTa

Cell typeParameterUnitValues
Day 11Day 15
PBS (n = 3)GRFT (n = 5)PBS (n = 3)GRFT (n = 5)
LeukocyteWBCk/μl4.92 ± 2.432.15 ± 0.234.35 ± 1.282.90 ± 1.36
NEk/μl2.30 ± 1.460.96 ± 0.131.67 ± 0.451.01 ± 0.42
LYk/μl2.49 ± 1.111.14 ± 0.282.60 ± 0.891.82 ± 0.99
MOk/μl0.09 ± 0.100.03 ± 0.030.07 ± 0.030.06 ± 0.04
EOk/μl0.03 ± 0.020.02 ± 0.010.02 ± 0.010.01 ± 0.02
BAk/μl0.00 ± 0.010.00 ± 0.000.00 ± 0.000.00 ± 0.00
ErythrocyteRBCM/μl4.30 ± 0.064.12 ± 0.184.75 ± 0.214.37 ± 0.22
Hbg/dl12.23 ± 0.6411.64 ± 0.4613.10 ± 0.4612.22 ± 0.61
HCT%38.30 ± 2.3136.12 ± 1.4741.57 ± 1.7639.52 ± 1.94
MCVfl88.97 ± 4.7387.58 ± 1.2987.53 ± 1.7090.40 ± 0.52*
MCHpg28.43 ± 1.3328.26 ± 1.5227.63 ± 0.6127.96 ± 1.04
MCHCg/dl31.97 ± 0.2532.26 ± 1.3331.50 ± 0.2630.94 ± 1.11
RDW%13.83 ± 1.4312.92 ± 0.7314.13 ± 0.2912.66 ± 0.70*
ThrombocytePLTk/μl595.33 ± 54.31628.60 ± 44.77677.33 ± 11.93659.00 ± 34.26
MPVfl4.40 ± 1.143.92 ± 0.233.57 ± 0.123.84 ± 0.24
  • a Data represent the mean values ± standard deviations for white blood cells (WBC), neutrophils (NE), lymphocytes (LY), monocytes (MO), eosinophils (EO), basophils (BA), red blood cells (RBC), hemoglobin (Hb), hematocrit (HCT), mean corpuscular volume (MCV), mean cell hemoglobin (MCH), mean cell hemoglobin concentration (MCHC), red cell distribution width (RDW), platelets (PLT), and mean platelet volume (MPV). Statistical significance (P < 0.05) is indicated by asterisks (*).