TABLE 2

SNPs identified in Pfmrp2 by sequencing the Thai isolates

Chromosome positionaNucleotide positionNucleotide changeAmino acid positionAmino acid changeFrequency (proportion)Location
1198644561T → A187Synonymous0.02 (1/46)TM2
1198610*#595C → G199L → V1.00 (46/46)TM2
1198321884C → G295T → R0.02 (1/46)loop
1198275930G → T310L → F0.02 (1/46)loop
1198224981C → T327Synonymous0.02 (1/46)loop
1197428*§1777A → G593N → D0.07 (3/46)NBD1
1197341*1864A → G622N → D0.22 (10/46)NBD1
1197064*§#2141A → T714K → I1.00 (46/46)NBD1
1196808*§2397C → T799Synonymous0.39 (16/41)NBD1
1195791*§3414T → C1138Synonymous0.20 (9/44)NBD1
1194626*#4579T → A1527S → T1.00 (46/46)TM9
1194614*#4591C → A1531L → I1.00 (46/46)TM9
11940935112T → C1704Synonymous0.02 (1/46)NBD2
11939545251A → T1751N → Y0.09 (3/34)NBD2
1193947§5258T → C1753F → S0.07 (3/46)NBD2
11938825323A → G1775I → V0.14 (5/36)NBD2
11938615344A → T1782M → L0.02 (1/46)NBD2
11938205385A → T1795Synonymous0.08 (3/37)NBD2
  • a Symbols: *, SNP previously registered with PlasmoDB; §, SNP previously found by deep sequencing of 227 samples from Africa, Asia, and Oceania (30); #, SNP previously described in reference 31.