TABLE 3

Characteristics of patients with carbapenemase-producing K. pneumoniae bloodstream infections according to treatment regimen

CharacteristicResult for patients on:P
Monotherapy (n = 72)Combination therapy (n = 103)
Age, mean yr (SD)66.5 (14.4)58.4 (19.5)0.002
Gender, no. (%)0.846
    Male43 (59.7)60 (58.3)
    Female29 (40.3)43 (41.7)
Ward at onset of BSI, no. (%)0.427
    Non-ICU33 (45.8)41 (39.8)
    ICU39 (54.2)62 (60.2)
Charlson comorbidity index, median (IQR)2 (0–3)2 (0–3)0.474
Severity of underlying disease, no. (%)0.376
    Rapidly fatal18 (25.0)17 (16.5)
    Ultimately fatal16 (22.2)27 (26.2)
    Nonfatal38 (52.8)59 (57.3)
Neutropenia, no. (%)0.483
    No65 (90.3)96 (93.2)
    Yes7 (9.7)7 (6.8)
Source of BSI, no. (%)0.333
    Non-urinary tract65 (90.3)97 (94.2)
    Urinary tract7 (9.7)6 (5.8)
Polymicrobial BSI, no. (%)0.418
    No55 (76.4)73 (70.9)
    Yes17 (23.6)30 (29.1)
Severity of sepsis, no. (%)0.629
    Sepsis49 (68.1)73 (70.9)
    Severe sepsis8 (11.1)14 (13.6)
    Septic shock15 (20.8)16 (15.5)