TABLE 5

Cox proportional hazards model of factors associated with all-cause 28-day mortality in 175 patients with carbapenemase-producing K. pneumoniae bloodstream infections

VariableHR (95% CI)P
Age (per 1-yr increase)1.01 (0.99–1.03)0.198
Gender (female/male)1.45 (0.82–2.55)0.198
Severity of underlying disease
    Ultimately fatal/nonfatal3.25 (1.51–7.03)0.003
    Rapidly fatal/nonfatal4.20 (2.19–8.08)<0.001
Charlson comorbidity index1.01 (0.85–1.20)0.879
Severity of sepsis
    Severe sepsis/sepsis1.63 (0.74–3.59)0.227
    Septic shock/sepsis2.15 (1.16–3.96)0.015
Polymicrobial bacteremia
    Yes/no1.29 (0.74–2.23)0.371
Ward at onset of bacteremia
    ICU/non-ICU1.36 (0.72–2.57)0.342
Monotherapy/combination therapy2.08 (1.23–3.51)0.006