TABLE 2

Analytical lower limits of quantitation for biological samples (15, 18, 25)

Sample matrixLLOQ (ng ml−1)
TDFTFVFTCMVC
Vaginal fluid10501010
CVL fluid1511
Vaginal tissue homogenatea5551
Plasma5551
  • a Assumes that vaginal tissue has a density of 1 g ml−1 (59).