TABLE 1

MIC and MBC data for EMRSA-16 NCTC 13143 and S. epidermidis ATCC 35984 in planktonic and biofilm growtha

Strain and antibioticsPlanktonic growth data (μg/ml)Biofilm growth data (MBC [μg/ml])
MICMBC
EMRSA NCTC 13143
    Tobramycin>5,000>5,000>5,000
    Vancomycin22>15,000
    Vancomycin-tobramycin2/0.482/0.48>15,000/3,600
S. epidermidis ATCC 35984
    Tobramycin64256>5,000
    Vancomycin24>15,000
    Vancomycin-tobramycin2/0.484/0.96>15,000/3,600
  • a Planktonic assays were performed in triplicate, and the data are expressed as the means of 15 data points (5 points per experimental repeat). Biofilm MBCs were determined in duplicate, and the data are expressed as the means of 10 data points (5 points per experimental repeat).