TABLE 3

Summary statistics for BC-3781 PK exposure estimates and half-life

Parameter and dose (mg)Mean (SD)Median (min, max)
Day 1 Cmax (μg/ml)
    1001.57 (0.974)1.46 (0.515, 8.11)
    1501.90 (0.705)1.88 (0.633, 4.38)
Day 1 AUC0–24 (μg · h/ml)
    10010.9 (5.97)9.87 (3.86, 48.3)
    15014.1 (5.76)12.8 (4.29, 35.1)
Half-life (h)
    10011.0 (5.18)9.74 (0.838, 23.5)
    15013.2 (5.79)12.4 (3.38, 23.5)