TABLE 1

Subject demographic characteristics of the PK analysis population

Variable100-mg group (n = 64)150-mg group (n = 65)All patients (n = 129)
No. (%)Mean no. (CV [%])Median (min-max)No. (%)Mean no. (CV [%])Median (min-max)No. (%)Mean no. (CV [%])Median (min-max)
Age (yr)41.3 (12.7)41.0 (18.0–73.0)42.0 (13.4)42.0 (20.0–73.0)41.6 (13.0)41.0 (18.0–73.0)
Wt (kg)89.0 (20.6)85.1 (43.8–146)95.6 (23.4)89.1 (46.4–161)92.3 (22.2)87.5 (43.8–161)
Ht (cm)173 (10.5)174 (152–191)173 (9.70)173 (150–196)173 (10.0)173 (150–196)
BSA (m2)2.07 (0.258)2.04 (1.51–2.71)2.15 (0.286)2.10 (1.41–2.81)2.11 (0.274)2.05 (1.41–2.81)
BMI (kg/m2)30.0 (7.53)29.2 (12.1–53.7)32.1 (7.82)31.4 (19.4–55.5)31.1 (7.73)30.3 (12.1–55.5)
CLCR (ml/min/1.73 m2)122 (33.3)118 (49.6–207)114 (32.5)113 (35.6–181)118 (33.0)117 (35.6–207)
Serum albumin level (g/liter)42.1 (4.62)42.0 (28.0–52.0)41.6 (4.47)42.0 (29.0–50.0)41.9 (4.54)42.0 (28.0–52.0)
No. (%) of males43 (67.2)43 (66.2)86 (66.7)
No. (%) of females21 (32.8)22 (33.9)43 (33.3)
No. (%) of Caucasians52 (81.3)45 (69.2)97 (75.2)
No. (%) of blacks7 (10.9)13 (20.0)20 (15.5)
No. (%) of Asians01 (1.54)1 (0.775)
No. (%) of Native American/Alaskan Natives2 (3.13)4 (6.15)6 (4.65)
No. (%) of Native Hawaiians/Pacific Islanders2 (3.13)2 (3.08)4 (3.10)
No. (%) of mixed race1 (1.56)01 (0.775)