TABLE 5

Median plasma cadazolid concentrations by treatment group

ParameterCadazolid
250 mg BID500 mg BID1,000 mg BID
First dose
    Median plasma cadazolid concn (mg/liter)0.000460.000650.00103
    No. of patients202020
    RangeBLQa–0.00216BLQ–0.00159BLQ–0.00530
Day 5/6 of treatment
    Median plasma cadazolid concn (mg/liter)0.001220.001460.00205
    No. of patients202119
    RangeBLQ–0.003870.00065–0.00461BLQ–0.01890
Last dose of treatment
    Median plasma cadazolid concn (mg/liter)0.000890.001620.00207
    No. of patients192119
    RangeBLQ–0.00272BLQ–0.004170.00073–0.01390
  • a BLQ, below the limit of quantification.