Table 2

Sulbactam activities against recent clinical strains of A. baumannii

Strainβ-Lactamase contentMIC (μg/ml)a
SULUNAMEMCSTLVXGENTET
ARC3491bOXA-2150.5120.5124
ATCC 19606TOXA-981210.50.2582
ARC2582OXAc120.250.1250.12542
ARC2597bOXAc120.1250.125<0.030.251
ARC2058OXA-95220.250.50.12511
ARC2728bOXAc220.250.250.1250.251
ARC5090OXAc220.250.250.1250.252
ARC2719OXAc240.250.1250.1250.52
ARC2720bOXAc2410.12520.52
ARC3489OXA,c OXA-682840.2516>32>32
ARC3494OXA-65420.250.50.250.252
ARC2780bOXA,c OXA-2, IMP-1443244>322
ARC3487OXA-20, OXA-58, OXA-664880.258816
ARC3659OXA-23, OXAc4880.258>328
ARC5084IMP-4(B), OXA-58, OXA-6548>320.1254>322
ARC2682SHV-5, OXA-113416320.2516>328
ARC2059PSE-2, PSE-18160.50.25>3214
ARC5092OXA-23, OXA-6481616>328>3232
ARC3485OXA-82832160.2516132
ARC2674SHV-5, OXA-11383280.25168>32
ARC2788OXA-65, TEM-183210.12532164
ARC3515OXA-64, OXA-5883240.2584>32
ARC5081OXA-94, OXA-23832160.12580.252
ARC5091OXA-82, OXA-23832328>32>3232
ARC2777OXA-172, TEM-18>32320.5321632
ARC3488OXA,c OXA-6816164232>32>32
ARC5075SHV-5, OXA-1131616320.2532>32>32
ARC5088OXA-20, OXA-58, OXA-66161680.1258816
ARC2675SHV-5, OXA-1131632>320.12532>3216
ARC2681OXA-40, TEM-1, OXA-1321632320.2516>32>32
ARC2778OXA-40, TEM-1, OXA-651632>320.2532>32>32
ARC2779bOXA-2, VIM-21632160.250.125>322
ARC3484TEM-1, OXA-23, OXA-641632320.1258>32>32
ARC3492OXA-40, OXA-132, TEM-11632>320.258>32>32
ARC3513TEM-1, OXA-23, OXA-65163232116>328
ARC5073OXA-23, TEM-1, OXA-64, PER-11632>320.12580.5>32
ARC5083OXA-66, OXA-231632160.125>32>32>32
ARC2461OXA-66, TEM-116>3220.12516>32>32
ARC2462TEM-1, OXA-6616>3240.12516>32>32
ARC2598OXA,c TEM-1, OXA-11316>3280.2542>32
ARC2635OXA-65, OXA-40, TEM-13232>320.2516>328
ARC5085OXA,c TEM-132328132>32>32
ARC3657OXA-13032>3220.5160.258
ARC2636OXA-65, OXA-40, TEM-132>32>320.12516>3216
ARC2782OXA-66, OXA-23, TEM-1, PER-132>32160.1254>32>32
ARC3486OXA-72, OXA-66, TEM-132>32>320.258>32>32
ARC3490TEM-1+, PSE-2, OXA-6932>320.50.516168
ARC3495OXA-40, OXA-10932>32>320.254>32>32
ARC3658OXA-66, PER-1, TEM-1, OXA-2332>32320.258>32>32
ARC5076TEM-1, OXA-23, OXA-6632>32320.2588>32
ARC5077OXA,c OXA-7232>32>320.516>32>32
ARC5079OXA-72, OXA-6532>32>320.1251688
ARC5080OXA-71, OXA-4032>32>320.2516>3216
ARC5086OXA,c TEM-1, OXA-72, OXA-6632>32>320.12516>32>32
ARC5087OXA-66, OXA-2332>32160.25>32>32>32
ARC5089PER,c TEM-1, OXA-23, OXA-6632>32320.12516>324
ARC3493OXA-40, OXA-6664>32>32324>32>32
ARC5074GES,c TEM-1, OXA-5164>3280.12540.1251
ARC5082OXA-66, OXA-2364>32>320.580.5>32
ARC3882OXA-23, NDM-1, OXA-10c>64>32>320.1254>328
Range0.5 to >641 to >32<0.03 to >320.125 to >32<0.03 to >320.06 to >320.5 to >32
  • a SUL, sulbactam; UNA, Unasyn (2:1 combination of ampicillin and sulbactam); MEM, meropenem; CST, colistin; LVX, levofloxacin; GEN, gentamicin; TET, tetracycline.

  • b Member of the A. baumannii-A. calcoaceticus complex family.

  • c The gene encodes a closely related variant of the indicated β-lactamase family.