TABLE 1

Tissue penetration of hooves inoculated with dermatophytes

Days of fungal growthTissue penetration (μm) ofa:
HPCH-based nail solution40% urea70% isopropyl alcoholUntreated control
TMTRTMTRTMTRTMTR
1000000<250
32501000500500
5<25<25175150175150150125
7<2575225175250200100250
9<25100175200NSb200275225
11150100150200200200NS150
13175125250NS275200300NS
15225100225225300225300150
  • a TM, T. mentagrophytes; TR, T. rubrum.

  • b NS, no sample; damaged during processing.