TABLE 1

Antibiotic susceptibility profiles of NDM-carrying clinical isolates, transconjugants, and transformants

AntibioticMIC (mg/liter) for NDM-carrying clinical isolate, transconjugant, and transformant:
JN247 (NDM-1)JN49 (NDM-14)JN49-J53JN247-J53J53DH5α(pHSG398)DH5α(pHSG398-NDM-1)DH5α(pHSG398-NDM-14)DH5α(pHSG398-NP-NDM-1)DH5α(pHSG398-NP-NDM-14)
Ampicillin>256>256>256>25642>256>256>256>256
Ceftazidime>256>256>256>2560.250.253232>256>256
Cefotaxime>256>256>256>25621128128>256>256
Meropenem≥32≥32420.0230.0230.0940.094416
Imipenem≥32≥32210.190.190.250.38616
Aztreonam8>2560.0620.0620.0620.0620.0620.0620.0620.062
Amikacin2160.0620.0620.0310.0310.0620.0620.0620.062
Ciprofloxacin420.0310.0310.0310.0310.0310.0310.0310.031
Tigecycline0.1250.1250.0150.0150.0150.0150.0150.0150.0150.015
Colistin110.250.1250.0620.0150.0150.0150.0310.031