TABLE 1

Trials providing parasite samples for analysis

TrialDatesAge (median [range]) (mo)Treatment for uncomplicated malariaChpraNo. of samples for which data were available for:HIV statusReference
IC50sSNPsIC50 and SNPs
PROMOTE-1May 2010–November 201243 (10–100)ALTS643837Infected33
PROMOTE-3June 2010–June 201318 (4–36)ALNone232249162Not infected11
TS6213454
SP6415160
DP3711634
Total459688347
  • a Chpr, chemoprevention; TS, trimethoprim-sulfamethoxazole; SP, sulfadoxine-pyrimethamine; DP, dihydroartemisinin-piperaquine. None, samples from subjects in chemoprevention arms collected before or after the intervention.