TABLE 3

Associations between putative virulence genes of hVISA isolates and treatment outcomes for patients

Gene product category and gene nameNo. (%) in whom gene was detectedP value
Deceased patients (n = 38)Surviving patients (n = 83)All patients (n = 121)
Adhesins
    fnbA38 (100)83 (100)121 (100)NAa
    fnbB38 (100)83 (100)121 (100)NA
    bbp37 (97.4)79 (95.2)116 (95.9)0.599
    ebpS36 (94.7)80 (96.4)116 (95.9)0.679
    map/eap1 (2.6)13 (15.7)14 (11.6)0.020
    sdrC35 (92.1)72 (86.7)107 (88.4)0.545
    sdrD36 (94.7)77 (92.8)113 (93.4)>0.999
    sdrE35 (92.1)80 (96.4)115 (95.0)0.377
    clfA38 (100)83 (100)121 (100)NA
    clfB38 (100)83 (100)121 (100)NA
    cnaNA
Toxins
    sea3 (7.9)12 (14.5)15 (12.4)0.385
    sebNA
    sec30 (78.9)52 (62.7)82 (67.8)0.075
    sedNA
    seeNA
    seg37 (97.4)70 (84.3)107 (88.4)0.062
    sehNA
    sei36 (94.7)68 (81.9)104 (86.0)0.060
    sejNA
    sek3 (7.9)11 (13.3)14 (11.6)0.545
    sel32 (84.2)62 (74.7)94 (77.7)0.243
    sem34 (89.5)71 (85.5)105 (86.8)0.553
    sen36 (94.7)71 (85.5)107 (88.4)0.221
    seo36 (94.7)71 (85.5)107 (88.4)0.221
    sep2 (2.4)2 (1.7)>0.999
    seq1 (2.6)10 (12.0)11 (9.1)0.170
    etaNA
    etbNA
    lukE-lukD38 (100)81 (97.6)119 (98.3)>0.999
    tst29 (76.3)57 (68.7)86 (71.1)0.390
    hla37 (97.4)79 (95.2)116 (95.9)>0.999
    hlb28 (73.7)49 (59.0)77 (63.6)>0.999
    hld36 (94.7)77 (92.8)113 (93.4)>0.999
    hlgNA
    hlg-238 (100)78 (94.0)116 (95.9)0.324
    pvlNA
Other putative virulence genes
    icaA38 (100)83 (100)121 (100)NA
    edinNA
  • a NA, not applicable.