TABLE 1

Description of 17 patients with monomicrobial Acinetobacter calcoaceticus-Acinetobacter baumannii complex bacteremia treated with tigecycline within 2 days of bacteremia onset

No.SexaAge (yr)APACHE II scoreOrigin of bacteremiabSpeciesTG MIC (mg/liter)cDuration of TG treatment (days)Concomitant appropriate antibioticdOutcome
Day 14Day 28
1M8727PneumoniaA. nosocomialis220NoneAliveAlive
2M5333PneumoniaA. baumannii215Ampicillin-sulbactamDeadDead
3M7625PneumoniaA. baumannii27NoneAliveAlive
4F7614PneumoniaA. nosocomialis1.512SulbactamAliveAlive
5M8326PneumoniaA. baumannii1.525NoneAliveAlive
6M8029PneumoniaA. baumannii1.512LevofloxacinDeadDead
7M7129PneumoniaA. baumannii1.59NoneDeadDead
8F6316PneumoniaA. nosocomialis0.28NoneAliveAlive
9M8938IAIA. baumannii1.56NoneDeadDead
10M6233PneumoniaA. nosocomialis0.531NoneAliveAlive
11M8033PneumoniaA. baumannii24NoneDeadDead
12M8332UTIA. baumannii214NoneAliveDead
13M8022PneumoniaA. baumannii1.59NoneAliveAlive
14F4519CR-BSIA. pittii0.18CeftazidimeAliveAlive
15F8423PneumoniaA. baumannii219NoneDeadDead
16M8326PneumoniaA. nosocomialis0.117NoneAliveAlive
17F6131PneumoniaA. baumannii1.54NoneDeadDead
  • a M, male; F, female.

  • b IAI, intra-abdominal infection; UTI, urinary tract infection; CR-BSI, catheter-related bloodstream infection.

  • c Tigecycline (TG) MIC was determined by Etest.

  • d Concomitant appropriate antibiotic was defined as intravenous antibiotic, to which the bacterium was susceptible, administered at an appropriate dose within 2 days of the bacteremia onset.