TABLE 1

Campynexin effectiveness on different bacterial species

StrainCompound EC50 (μM)a
CCG-84443CCG-187741CCG-187751CCG-187769CCG-198215
C. jejuni DRH21212.939.8316.142.9551.78
C. jejuni MTVDSCj203.998.0812.682.7250.06
C. coli MTVDSCc17.5516.815.43.8237.54
E. coli EC2880 ΔtolC>100>100>100>100>100
H. pylori J75>100>100>100>100>100
  • a The EC50 was calculated from a dose-response curve that was generated from the average result for triplicate cultures at the given concentrations.