TABLE 2

Antimicrobial susceptibilities of the eight NDM-producing K. pneumoniae isolates

CaseSample typeSTResistance mechanismsMIC(s) (mg/liter) ofa:
AMCSAMPIPCAZCTXCROFEPIPMMEMLVXCIPAMKGEN
1Blood17NDM-1, TEM-1, CTX-M-15, CMY-4, SHV-1, qnrS>16/8>16/8>64>16>32>32>16≥8>8≤2≤1≤16≤1
2Blood17NDM-1, TEM-1, CTX-M-15, CMY-4, SHV-1, qnrS>16/8>16/8>64>16>32>32>16≥8>8≤2≤1≤16≤1
3Sputum17NDM-1, TEM-1, CTX-M-15, CMY-4, SHV-1, qnrS>16/8>16/8>64>16>32>32>16≥8>8≤2≤1≤16≤1
4Sputum17NDM-1, TEM-1, CTX-M-15, CMY-4, SHV-1, qnrS>16/8>16/8>64>16>32>32>16≥8>8≤2≤1≤16≤1
5Blood17NDM-1, TEM-1, CTX-M-15, CMY-4, SHV-1, qnrS>16/8>16/8>64>16>32>32>16≥8>8≤2≤1≤16≤1
6Sputum17NDM-1, TEM-1, CTX-M-15, CMY-4, SHV-1, qnrS>16/8>16/8>64>16>32>32>16≥8>8≤2≤1≤16≤1
7Sputum433NDM-1, TEM-1, OXA-2>16/8>16/8≤16>16>32>32>1648≤2≤1≤16≤1
8Sputum17NDM-1, TEM-1, CTX-M-15, CMY-4, SHV-1, qnrS>16/8>16/8>64>16>32>32>16≥8>8≤2≤1≤16≤1
  • a AMC, amoxicillin-clavulanic acid; SAM, ampicillin-sulbactam; PIP, piperacillin; CAZ, ceftazidime; CTX, cefotaxime; CRO, ceftriaxon; FEP, cefepime; IPM, imipenem; MEM, meropenem; LE, levofloxacin; CI, ciprofloxacin; AM, amikacin; GE, gentamicin.