TABLE 4

Protein-denaturing effects of olanexidine on hemoglobin by concentrationa

Test substanceHDR% for concn (μg/ml) of:
9.819.539.178.11563136251,2502,5005,00010,000
Olanexidine gluconate−1.5 ± 3.3−2.6 ± 2.90.7 ± 2.70.8 ± 2.515.0 ± 3.136.1 ± 1.945.3 ± 1.646.2 ± 1.347.8 ± 1.948.4 ± 1.647.7 ± 1.5
Chlorhexidine digluconate−0.1 ± 1.80.2 ± 1.1−1.8 ± 0.5−1.7 ± 1.9−1.2 ± 2.4−3.1 ± 2.3−2.4 ± 1.6−1.6 ± 1.8−0.9 ± 1.0−1.8 ± 2.34.4 ± 0.4
Hexadecyl-pyridinium chloride monohydrate (positive control) (25)0.8 ± 1.25.9 ± 0.77.0 ± 0.820.8 ± 0.938.9 ± 0.838.5 ± 0.837.9 ± 1.037.4 ± 0.738.1 ± 0.738.5 ± 1.339.8 ± 1.1
  • a Values represent the mean ± SD (n = 4).