TABLE 1

Selected antibiotics tested against B. burgdorferi

DrugClassMIC (μg/ml)aMaximum serum concn (μg/ml)Reference
Amoxicillinβ-Lactam0.067.657
CeftriaxoneCephalosporin0.01256.958
DoxycyclineTetracycline0.252.6–5.959
GemifloxacinFluoroquinolone0.1252.3338
SpectinomycinAminoglycoside2140–16041
DaptomycinLipopeptide12.5–2555–13360
VancomycinGlycopeptide0.254061
Mitomycin CAntitumor antibiotic0.23.262
  • a The MIC was determined by the broth microdilution method.