TABLE 4

Univariate and multivariate logistic regression analyses to identify independent predictors of AKI by KDIGObin, NT0.5, and NT2×

AKI criteria predictorsaUnivariate analysis (OR [95% CI])P valuebMultivariate analysis (OR [95% CI])P valueb
KDIGObin
    Age (yr)1.02 (1.00–1.04)0.0661.02 (1.00–1.04)0.096
    Deoxycholate preparation1.24 (0.61–2.52)0.553
    ICU initiation1.24 (0.53–2.91)0.618
    Leishmaniasis1.40 (0.69–2.85)0.353
    Charlson index ≥41.28 (0.61–2.71)0.519
    Furosemide2.26 (1.01–5.07)0.0472.30 (0.98–5.39)0.056
    ACE-I2.29 (0.91–5.77)0.080
    Polymyxin B0.59 (0.22–1.63)0.309
    Vancomycin1.22 (0.64–2.32)0.540
    Vasopressors1.07 (0.50–2.30)0.854
NT0.5
    Age (yr)1.02 (1.00–1.04)0.0641.02 (1.00–1.04)0.038
    Deoxycholate preparation1.93 (0.93–4.03)0.078
    ICU initiation1.99 (0.86–4.61)0.108
    Leishmaniasis0.85 (0.43–1.71)0.653
    Charlson index ≥41.13 (0.55–2.34)0.744
    Furosemide2.13 (1.01–4.49)0.048
    ACE-I1.66 (0.72–3.81)0.233
    Polymyxin B0.84 (0.30–2.32)0.734
    Vancomycin2.01 (1.06–3.81)0.0322.24 (1.16–4.32)0.016
    Vasopressors1.61 (0.76–3.41)0.218
NT2×
    Age (yr)1.00 (0.98–1.02)0.965
    Deoxycholate preparation2.32 (0.94–5.69)0.067
    ICU initiation2.47 (1.05–5.81)0.038
    Leishmaniasis0.47 (0.20–1.10)0.082
    Charlson index ≥41.27 (0.58–2.81)0.550
    Furosemide1.85 (0.85–4.02)0.080
    ACE-I1.68 (0.70–4.02)0.243
    Polymyxin B1.09 (0.36–3.30)0.874
    Vancomycin2.74 (1.35–5.54)0.0052.27 (1.09–4.72)0.028
    Vasopressors3.34 (1.52–7.32)0.0032.73 (1.21–6.16)0.015
  • a Age was evaluated as a continuous variable; all other independent variables are categorical.

  • b Variables with a P value of <0.20 in univariate analyses (in bold type) were included in a multivariate backward logistic regression model. Only the variables remaining at the final model are shown.