TABLE 6

Impact of AKI on ICU admission, mechanical ventilation, and inpatient mortalitya

AKI criteria by outcomebAKI by binary criteriaAKI by KDIGO stage
No AKIAKIP valueNo AKIStage 1Stage 2Stage 3P value
ICU admission20/67 (29.9)8/50 (16.0)12/30 (40.0)13/15 (86.7)<0.001
    NT2×28/117 (23.9)24/45 (55.6)<0.001
    NT0.522/89 (24.7)31/73 (42.5)0.017
    KDIGObin20/67 (29.9)33/95 (34.7)0.514
Mechanical ventilation15/67 (22.4)7/50 (14.0)10/30 (33.3)11/15 (73.3)<0.001
    NT2×22/117 (18.8)21/45 (46.7)<0.001
    NT0.516/89 (18.0)27/73 (37.0)0.006
    KDIGObin15/67 (22.4)28/95 (29.5)0.314
Inpatient mortality16/67 (23.9)9/50 (18.0)9/30 (30.0)11/15 (73.3)<0.001
    NT2×25/117 (21.4)20/45 (44.4)0.003
    NT0.519/89 (21.3)26/73 (35.6)0.044
    KDIGObin16/67 (23.9)29/95 (30.5)0.352
  • a Other than P values, data are presented as the no./total no. (%).

  • b NT2×, traditional nephrotoxicity criterion of an SCr increase of ≥2× over baseline; NT0.5, traditional nephrotoxicity criterion of an absolute SCr increase of ≥0.5 mg/dl over baseline; KDIGO, Kidney Diseases Improving Global Outcomes; KDIGObin, absolute SCr increase of ≥0.3 mg/dl or ≥1.5× over baseline.