TABLE 7

Impact of AKI criteria on the univariate association between AKI and mortality

AKI criteria by regression methodaNo./total no. (%)OR/HR (95% CI)bP value
Univariate logistic regression
    Binary
        NT0.526/73 (35.6)2.04 (1.02–4.09)0.045
        NT2×20/45 (44.4)2.94 (1.41–6.14)0.004
        KDIGObin29/95 (30.5)1.40 (0.69–2.85)0.353
    KDIGO stage
        19/50 (18.0)0.70 (0.28–1.75)0.444
        29/30 (30.0)1.37 (0.52–3.57)0.525
        311/15 (73.3)8.77 (2.45–31.36)0.001
    Dialysis10/11 (90.9)33.14 (4.10–267.98)<0.001
Univariate Cox regression
    Binary
        NT0.526/73 (35.6)1.53 (0.84–2.81)0.168
        NT2×20/45 (44.4)2.23 (1.23–4.03)0.008
        KDIGObin29/95 (30.5)1.20 (0.65–2.24)0.559
    KDIGO stage
        19/50 (18.0)0.62 (0.26–1.46)0.270
        29/30 (30.0)1.19 (0.52–2.72)0.682
        311/15 (73.3)3.29 (1.52–7.13)0.002
    Dialysis10/11 (90.9)5.05 (2.47–10.34)<0.001
  • a NT2×, traditional nephrotoxicity criterion of an SCr increase of ≥2× over baseline; NT0.5, traditional nephrotoxicity criterion of an absolute SCr increase of ≥0.5 mg/dl over baseline; KDIGO, Kidney Diseases Improving Global Outcomes; KDIGObin, absolute SCr increase of ≥0.3 mg/dl or ≥1.5× over baseline.

  • b Odds ratio (OR) was used for logistic regression data and hazard ratio (HR) for Cox regression data. 95% CI, 95% confidence interval.