TABLE 4

Pharmacokinetic parameters of AQ and DAQ in 6 patients with falciparum malaria who received FDC AQAS (612/200 mg for 3 days)

SubjectAQDAQ
Cmax (ng/ml)Tmax (h)T1/2 (h)AUC0–t (h · ng/ml)Cmax (ng/ml)Tmax (h)T1/2 (h)AUC0–t (h · ng/ml)
12520.507.261,08454948211107,766
22741.007.391,03172948213116,125
32560.5010.61,00194248212138,628
42371.007.701,03355348213107,182
52770.507.831,07685848214123,218
62671.0011.198688948215128,846
Meana2610.758.651,03575348213120,294
SD15.10.271.7439.31721.3312,362
  • a Mean pharmacokinetic parameters of AQ and DAQ for 6 patients with SD.