TABLE 1

β-Lactamase production and OMP profiles for the 139 CNSE isolates

OMP profileOrganism with β-lactamase production, β-lactamase(s) (no. of strains)
CarbapenemaseESBLAmpCESBL + AmpCNo β-lactamase
Wild-type outer membrane profileE. cloacae, IMI-3 (1)M. morganii (3)P. mirabilis (1)
K. pneumoniae, OXA-48 (1)
Loss of one major outer membrane porinK. pneumoniae, CTX-M-15 (10)E. aerogenes (4)E. cloacae, CTX-M-9/SHV-12 (36)
E. coli, CTX-M-15 (2)E. cloacae (39)E. cloacae, CTX-M-9 (20)
C. freundii (4)E. cloacae, SHV-12 (4)
S. marcescens (1)C. freundii, CTX-M-9 (1)
E. coli, ACC-1 (1)
Loss of OmpC-like and OmpF-like porinsK. pneumoniae, CTX-M-15 (1)K. pneumoniae, CMY-2 (4)E. cloacae, CTX-M-9/SHV-12 (4)
S. marcescens (1)E. aerogenes, TEM-24 (1)