TABLE 1

Comparison of clinical factors in patients with and without culture conversion

ParameterValuea for patients with:P value
No culture conversion (n = 17)Culture conversion (n = 11)
Age, yr42 (17–81)42 (16–69)0.693
Gender
    Female7 (41)5 (45)0.823
    Male10 (59)6 (55)
HIV test
    Negative10 (59)6 (55)0.823
    Positive7 (41)5 (45)
Previous TB treatment
    Yes5 (29)5 (45)0.387
     No12 (71)6 (55)
Wt, kgb51.35 (26–64)52 (39–70)0.786
Amikacin therapy duration, days172.5 (28–320)207.5 (65–866)0.041
Amikacin dose, mg/kg17.44 (13.70–19.23)17.01 (11.11–19.23)0.961
Amikacin Cmax, mg/liter49.42 (22.02–65.59)49.42 (25.94–76.95)0.493
Amikacin AUC0–24, mg · h/liter556.91 (241.50–988.71)599.56 (446.34–766.91)0.371
Amikacin trough concn, mg/liter0.64 (0–11.89)0 (0–4.92)0.338
  • a Values are either number (%) of patients or median (range).

  • b Data for some patients are missing.