TABLE 2

Compound 1 MIC values against M. tuberculosis Erdman and monoresistant isolates compared with known standardsa

StrainMIC (μg/ml)
Compound 1PA-824RIFINHSTR
M. tuberculosis Erdman0.1270.1160.0180.2440.369
RIFr0.1200.128>40.3830.216
INHr0.059≤0.0630.037>80.202
STRr0.1130.1890.0820.344>16
  • a RIF, rifampin; INH, isoniazid; STR, streptomycin; RIFr, strain with resistance to rifampin.