TABLE 1

Baseline characteristics of hVISA and VSSA patients

ParameteraValue for the cohortP value
hVISA (n = 29)VSSA (n = 58)
Median age (yr [IQR])63.0 (56.0–76.0)59.00 (50.0–68.25)0.117
Median wt (kg [IQR])70.0 (63.5–87.5)69.9 (60.4–79.7)0.595
Median Charlson score (IQR)5 (2.5–7.0)5 (2.0–7.0)0.995
Median SOFA score (IQR)b7.0 (5.0–8.0)5 (3.0–8.0)0.092
No. (%) of female patients10 (34.5)24 (41.4)0.534
No. (%) of African American patients21 (72.4)40 (69.0)0.907
Clinical factors (no. of patients [%])
    Diabetes10 (34.5)22 (37.9)0.753
    History of CVA7 (24.1)16 (27.6)0.731
    Any respiratory pathology13 (44.8)33 (56.9)0.241
    HIV/AIDS2 (6.9)3 (5.2)0.745
    Liver disease2 (6.9)7 (12.1)0.455
    Intravenous drug use8 (27.6)11 (19.0)0.359
    Hemodialysis3 (10.3)4 (6.9)0.577
eGFR (median [IQR])
    Baseline60.0 (36.5–100.0)86.0 (60.0–115.5)0.022
    At start of antimicrobial treatment31.5 (17.3–68.0)62.0 (38.0–96.5)0.013
Prior hospitalization (no. of patients [%])15 (51.7)32 (55.2)0.761
Antibiotic use in the last 30 days (no. of patients [%])7 (24.1)7 (12.1)0.149
Admission data (no. of patients [%])
    Home19 (65.5)35 (60.3)0.851
    SNF8 (27.6)15 (25.9)1.000
  • a IQR, interquartile range; SOFA, sequential organ failure assessment; CVA, cerebrovascular accident; HIV, human immunodeficiency virus; eGFR, estimated glomerular filtration rate; SNF, skilled nursing facility.

  • b First 24 h after hospital admission.