TABLE 1

General features of IncA/C2 and IncFIIY plasmids studied here and close relativesa

PlasmidNDMSize (bp)SpeciesSTCountrybYrSourceGenBank accession no.Reference
A/C2
    pKP1-NDM-11137,552K. pneumoniae147India/Australia2010HumanKF992018This study
    pEC2-NDM-33160,989E. coli443India/Australia2010HumanKC999035This study
    pNDM-EcoGN5681166,750E. coli1289India/CanadanaHumanKJ80240450
    pNDM-PstGN5761147,886P. stuartiiN/AIndia/CanadanaHumanKJ80240550
    pNDM1023371165,974E. colinaCanadananaNC_019045
    pNDM105051166,744E. colinaCanadananaNC_019069
    pNDM104691137,813K. pneumoniaenaCanadananaNC_019158
    pNDM-KN1162,746K. pneumoniae14Kenya2009HumanJN15780451, 52
    pNDM-US1140,825K. pneumoniae11India/USA2010HumanCP00666153
    pNDM-US-21140,821K. pneumoniaenaKJ588779c
FIIY
    pECL3-NDM-1199,435E. cloacae265India/Australia2011HumanKC887917This study
    pEC4-NDM-66110,786E. coli101India/New Zealand2010HumanKC887916This study
    pKOX_NDM11110,781Klebsiella oxytocanaChina/Taiwan2010HumanNC_02150118
    pNDM1_EC146531109,353E. cloacae177China2014HumanKP86864743
    pNDM-EclGN5741110,786E. cloacaenaIndia/CanadanaHumanKJ81299850
    pP10164-NDM199,276Leclercia adecarboxylataN/AChina2012HumanKP90001619
    pRJF8661110,786K. pneumoniae11China2011HumanNC_02518454
    pK3511106,844K. pneumoniae147Iran/USA2014HumanKR35129041
  • a Plasmids with names in bold typeface were sequenced in this study. Abbreviations: na, not available; N/A, not applicable (no multilocus typing schemes for these species); ST, sequence type.

  • b Travel history is given if available, e.g., India/Australia indicates isolation in Australia from a patient recently returned from India.

  • c GenBank accession no. KJ588779 implies that pNDM-US-2 was extracted in China from the same strain (ATCC BAA-2146) as pNDM-US.