TABLE 2

FOR to TXA707 alone and in combination with cefdinir in clinical isolates of MRSA, VISA, VRSA, and LRSA

IsolateFOR to:
4 μg/ml TXA707 alone4 μg/ml TXA707 + 1 μg/ml cefdinir4 μg/ml TXA707 + 4 μg/ml cefdinir4 μg/ml TXA707 + 8 μg/ml cefdinir
MRSA (n = 13)
    MPW0116.31 × 10−81.89 × 10−8<9.01 × 10−10
    MPW0123.16 × 10−89.52 × 10−9<7.94 × 10−10
    MPW0132.84 × 10−82.79 × 10−9<5.68 × 10−10
    MPW0144.85 × 10−82.02 × 10−9<1.01 × 10−9
    MPW0151.10 × 10−82.20 × 10−91.10 × 10−9<1.10 × 10−9
    MPW0161.05 × 10−84.65 × 10−9<5.81 × 10−9
    MPW0175.26 × 10−87.55 × 10−9<3.77 × 10−9
    MPW0186.05 × 10−82.04 × 10−8<6.17 × 10−10
    MPW0192.89 × 10−81.02 × 10−8<8.51 × 10−10
    MPW0204.29 × 10−82.52 × 10−8<6.29 × 10−10
    R25271.24 × 10−8<1.55 × 10−9<1.55 × 10−9
    COL4.14 × 10−88.39 × 10−94.52 × 10−9<6.45 × 10−10
    ATCC 335914.64 × 10−88.47 × 10−97.91 × 10−96.78 × 10−9
VISA (n = 3)
    NRS49.14 × 10−88.62 × 10−10<4.31 × 10−10
    NRS276.32 × 10−8<4.37 × 10−10<4.37 × 10−10
    Mu39.87 × 10−83.44 × 10−8<2.15 × 10−9
VRSA (n = 2)
    VRS25.46 × 10−81.04 × 10−8<8.70 × 10−10
    VRS52.53 × 10−8<1.27 × 10−9<1.27 × 10−9
LRSA (n = 2)
    NRS1271.78 × 10−83.55 × 10−9<5.92 × 10−10
    NRS2718.03 × 10−83.01 × 10−81.92 × 10−8<9.13 × 10−10