Sensitivity, specificity, and positive and negative predictive values of vancomycin concentrations at T3 for predicting AUC0–24/MIC ratios of ≥400 at different MICsa

Vancomycin concn (mg/liter) at T3 and predictive measureValue (%) for predicting anAUC0–24/MIC ratio of ≥400 at a MIC (mg/liter) of:
  • a T3, 24 h after the initiation of therapy; AUC0–24/MIC ratio, ratio between the area under the curve of drug concentrations over the first day of therapy and the MIC.