TABLE 2

CART analysis-derived MIC clinical breakpoints for M. tuberculosis isolates from 207 MDR-TB patientsa

2nd drugSputum culture conversion after 4 moTreatment success
MIC CBP (mg/liter)SeSpMIC CBP (mg/liter)SeSp
Pyrazinamide18.750.7210.83537.50.8890.926
Ofloxacin30.6160.56730.6500.627
Levofloxacin50.9300.1741.50.9060.265
Capreomycin480.9770.10750.8800.250
Amikacin30.5230.661960.9830.118
Kanamycin960.9770.13260.6580.618
  • a Se, sensitivity; Sp, specificity.