TABLE 3

Univariate and multivariate analysis of factors associated with multidrug-resistant tuberculosis treatment outcome

Drug DST CC or CBPUnivariate logistic regression analysisMultivariate logistic regression analysisa
Sputum culture conversion after 4 moTreatment successSputum culture conversion after 4 moTreatment success
POR95% CIPOR95% CIPOR95% CIPOR95% CI
CART Model0.0000.080.04–0.150.0000.010.002–0.020.0000.070.04–0.150.0000.010.002–0.02
PZA CBP0.0000.080.04–0.150.0000.010.003–0.030.0000.070.04–0.150.0000.010.003–0.03
PZA DST CC0.0000.320.18–0.580.0000.240.13–0.450.0000.320.18–0.590.0000.230.12–0.45
OFX CBP0.0100.480.27–0.840.0000.320.17–0.600.0100.480.27–0.840.0000.300.15–0.57
OFX DST CC0.0030.270.11–0.650.0010.240.10–0.560.0030.270.11–0.650.0010.230.10–0.55
LVX CBP0.0340.360.14–0.930.0030.290.13–0.660.0320.350.13–0.910.0050.300.13–0.69
LVX DST CC0.2750.570.21–1.560.3881.810.47–6.910.2620.560.21–1.540.5541.510.38–5.98
CAP CBP0.0360.200.04–0.900.0250.410.19–0.890.0370.200.04–0.900.0150.360.16–0.82
CAP DST CC0.0040.110.03–0.500.9490.970.34–2.790.0030.110.03–0.480.6570.780.26–2.32
KAN CBP0.0150.160.04–0.700.0000.320.17–0.600.0150.160.04–0.690.0000.290.15–0.55
KAN DST CC0.0020.260.12–0.600.1730.610.30–1.240.0010.250.11–0.590.0710.500.24–1.06
AMK CBP0.0080.470.27–0.820.0120.130.03–0.630.0080.460.26–0.810.0190.150.03–0.73
AMK DST CC0.0060.310.14–0.720.0480.470.22–0.990.0060.310.13–0.710.0210.400.18–0.87
  • a Adjusted for the presence of pulmonary cavity and severe pulmonary disease on CXR.