TABLE 1

Initial and repeat LJ DST and MABA MIC results for the seven strains for which there was disagreement between the different methods during the initial round of testinga

StrainOFX LJ DST resultMABA MIC (μg/ml)Genotypeb
OFXAFXLFXMFXgyrAgyrB
14170R20.250.1250.125WTWT
S0.50.50.250.25
12657R210.50.25WTWT
S110.50.25
14130R20.50.250.125WTWT
S110.50.25
14132R0.50.50.1250.125WTWT
S10.50.50.25
14150R2210.5WTWT
S110.50.25
14175R20.50.250.125WTWT
S0.50.50.250.125
14198R2421D94AWT
R8842
14117S210.50.25WTT500N
S2210.5
  • a In each case, the repeat results are shown in Fig. 1 and listed in Table S1 in the supplemental material. MICs above the ECOFF (i.e., phenotypically non-wild-type results) are underlined. All of these discrepancies, which are shown in bold, were resolved upon retesting. In contrast, strain 14117 was retested because the initial MICs and the previous literature suggested that the MICs were close to the ECOFFs, which retesting supported.

  • b Excluding the gyrA S95T polymorphism. WT, wild type.