TABLE 1

Occurrence of mcr-1 among E. coli and K. pneumoniae clinical isolates collected worldwide during 2014 and 2015 as part of the SENTRY Antimicrobial Surveillance Programa

Organism(s) and location where mcr-1-positive isolate(s) was observedNo. of mcr-1-positive isolates/no. of colistin-resistant isolates (%)No. of mcr-1-positive isolates with colistin MICs (μg/ml) of:
48>8
All colistin-resistant organisms19/390 (4.9)1081
E. coli19/59 (32.2)1081
    Belgium (Antwerp)1/11
    Brazil (Florianopolis)1/11
    Germany (Bonn and Kiel)5/1023
    Hong Kong1/11
    Italy (Florence, Milan, and Rome)4/931
    Malaysia (Kelantan)1/11
    Poland (Warsaw)1/21
    Russia (Yekaterinburg)1/21
    Spain (Madrid)3/321
    USA (New York City)1/151
  • a All K. pneumoniae isolates were negative for mcr-1.