TABLE 2

In vitro antifungal susceptibility patterns of Scedosporium spp. and L. prolificans against azolesa

SpeciesTotal no. of isolatesICZPCZVCZ
nRangeMIC50MIC90GMnRangeMIC50MIC90GMnRangeMIC50MIC90GM
S. apiospermum81800.5 to >16>16>1614.5800.25 to >164>165.8810.25 to 4241.5
S. boydii26220.5 to >16>16>1611.3240.25 to >162>162.8260.125 to 4140.8
S. ellipsoideum24210.25 to >16>16>1614.0220.5 to >164>166.2240.25 to 4121.2
S. dehoogii1613>16>16>1632.0132 to >162>166.1130.5 to >161>162.4
S. aurantiacum73>1632.041 to >163.440.25 to >161.4
L. prolificans31>1632.02>1632.02>1632.0
  • a GM, geometric mean; ICZ, itraconazole; PCZ, posaconazole; VCZ, voriconazole.