TABLE 6

Excretion of parent omadacycline and total radioactivity in the BDC ratsa

Route of excretion, time of excretionAmt excreted (% of dose)
RadioactivityOmadacycline
Bile, 0–24 h28.6 ± 2.5527.3
Bile, 0–48 h29.6 ± 2.47
Feces, 0–24 h27.1 ± 9.93
Feces, 0–168 h35.4 ± 5.0830.2
Urine, 0–24 h39.1 ± 6.33
Urine, 0–48 h42.5 ± 7.2838.4
Total amt recovered109 ± 3.96
  • a All data are means ± standard deviations or means. ND, not detected.