TABLE 3

MIC and MBC values of CHD and CST after plasmid complementationa

StrainPlasmidDescriptionCHDCST
MIC (mg/liter)MBC (mg/liter)MIC (mg/liter)MBC (mg/liter)
M109 CApACYC-184 aloneEmpty vector32322–42–4
pACYC M3 smvR WTsmvR from strain M38822
pACYC M3 smvR CHDsmvR from strain M3 CA32322–42–4
pACYC 13443 smvR WTsmvR from strain NCTC 134438822
pACYC 13443 smvR CHDsmvR from strain NCTC 13443 CA32322–42–4
pACYC phoPQ WTphoPQ from strain NCTC 1344332–6432–641–22
pACYC phoQ A20PphoPQ from strain NCTC 13443 CA32–64646464–>64
M109 WTpACYC-184 aloneEmpty vector8–168–160.5–12–4
pACYC phoPQ WTphoPQ from strain NCTC 134438–168–320.5–12–4
pACYC phoQ A20PphoPQ from strain NCTC 13443 CA8–1616–3232–6464
25pACYC-184 aloneEmpty vector8–168–160.52–4
pACYC phoPQ WTphoPQ from strain NCTC 134438–1616–320.5–11–4
pACYC phoQ A20PphoPQ from strain NCTC 13443 CA8–1616–6432–6432–>64
  • a Levels of resistance to CHD and CST were measured after electroporation of the plasmids into the strains listed. All the MICs are shown as ranges of the results of at least three independent experiments.