TABLE 4

Comparison of susceptibilities of resistant isolates CREC01 and CREC02 before and after exposure to polymyxin B in an HFIM

AntibioticMIC (mg/liter) for strain:
CREC01CREC02
Before polymyxin B exposureAfter polymyxin B exposureBefore polymyxin B exposureAfter polymyxin B exposure
Amikacin≥128≥128≥128≥128
Levofloxacin≥6432≥64≥64
Rifampin≥64≥64≥64≥64
Polymyxin B28116
Tigecycline0.5≤0.250.50.5
Cefepime≥64≥64≥64≥64
Meropenem≥64≥643232
Doripenem≥16≥168≥16
Imipenem≥32≥32≥32≥32
Aztreonam≥128≥128≥128≥128
Piperacillin-tazobactam≥256/4≥256/4≥256/4≥256/4