TABLE 2

Baseline laboratory test results for children with TB with and without HIV coinfection

Characteristic (n)Median value (IQR) for groupP value
All (n = 113)TB (n = 54)TB/HIV (n = 59)
White blood cell count, 109/liter (72)8.6 (6.0–11.9)9.6 (6.4–11.9)7.7 (5.2–11.7)0.215
Absolute neutrophil count, 1,000 (65)3.2 (1.9–4.8)3.4 (2.2–5.7)2.8 (1.9–3.6)0.101
Hemoglobin, g/dl (73)9.5 (8.7–10.7)9.8 (9.3–11.0)9.3 (8.4–10.4)0.073
Hematocrit, % (70)29.2 (26.6–32.9)30.3 (28.4–34.0)28.2 (25.5–32.9)0.052
Platelets, 109/liter (72)316 (206.5–508.0)450.0 (275.0–587.0)276.0 (190.0–350.0)0.001
Sodium, mmol/liter (48)132 (127.5–135.5)133.0 (128.5–136.0)130.0 (127.0–133.5)0.007
Potassium, mmol/liter (46)4.1 (3.8–4.5)4.2 (3.9–4.5)4.1 (3.8–4.5)0.491
Blood urea nitrogen, mmol/liter 792.8 (1.9–3.7)2.6 (1.9–3.7)2.9 (1.9–3.6)0.632
Serum creatinine, μmol/liter (79)36.0 (27.0–50.0)35.3 (28.0–51.0)37.0 (23.0–47.0)0.199
Glomerular filtration rate, ml/min/1.73 m2 (77)102.4 (85.9–126.7)98.7 (85.9–115.3)103.4 (84.1–138.4)0.659
AST, U/liter (79037.0 (29.0–51.0)31.0 (25.0–40.0)43.6 (36.0–56.1)<0.001
ALT, U/liter (75)22.0 (15.2–36.0)19.0 (14.0–40.0)22.6 (18.0–34.0)0.062
Alkaline phosphatase, U/liter (77)386.0 (292.0–563.0)510.0 (340.0–637.0)370.0 (160.8–474.0)<0.001
Total bilirubin, μmol/liter (76)6.0 (4.3–9.0)7.0 (5.0–9.0)5.0 (4.0–8.0)0.412
Albumin, g/liter (79)38.0 (32.0–43.0)42.0 (38.0–43.0)34.0 (30.8–38.0)<0.001
HIV-related laboratory tests
    CD4 cells
        Count, cells/μl (46)460.0 (77.0–925.0)
        % (42)10.0 (6.0–18.0)
    HIV-1 RNA, copies/ml (34)267,912 (70,300–886,059)
    Log10 HIV-1 RNA (34)5.4 (4.8–5.9)
    HIV-1 RNA >100,000 copies/ml25 (73.5%)