TABLE 3

PAE results for time-kill curves for gepotidacin and comparator agents after 1 h of exposure at 1×, 5×, and 10× baseline MIC values

N. gonorrhoeae isolateGepotidacinCeftriaxone
Baseline MIC (μg/ml)PAE (h) at various MICsBaseline MIC (μg/ml)PAE (h) at various MICs
10×10×
ATCC 492260.250.51.0>2.50.0040.30.00.0
125840.120.70.70.70.0040.70.20.0