TABLE 1

Baseline characteristics of the study groups

CharacteristicResult for:P value
Children (n = 30)Adults (n = 30)
Sociodemographic
    Age (yr), mean (SD)8.16 (2.58)33.53 (8.32)
    Male gender, no. (%)18 (60)14 (46.67)0.3a
    Ethnicity, no. (%)0.76a
        Afro-Colombian22 (73.33)23 (76.67)
        Mestizo8 (26.67)7 (23.33)
    Study site, no. (%)0.57a
        Cali8 (26.67)10 (33.33)
        Tumaco22 (73.33)20 (66.67)
Clinical
    Wt (kg), mean (SD)26.22 (7.62)70.84 (11.73)
    No. of lesions, median (IQR)2 (1–3)1 (1–2)0.39b
    Time evolution of older lesion (mo), median (IQR)1 (1–2)2 (2–3)0.007b
    Hemoglobin (g/dl), mean (SD)12.7 (0.84)13.71 (1.57)0.002c
    Albumin (g/dl), mean (SD)4.50 (0.26)4.57 (0.27)0.33c
    Dose (mg/kg/day), mean (SD)2.27 (0.16)2.11 (0.32)0.02c
Lesions (n = 118)
    Type, no. (%)0.003d
        Ulcer54 (85.71)33 (60.00)
        Plaque7 (11.11)19 (34.55)
        Other2 (3.17)3 (5.45)
    Location, no. (%)0.35a
        Face-neck11 (17.46)6 (10.91)
        Trunk9 (14.29)9 (16.36)
        Arms21 (33.33)26 (47.27)
        Legs22 (34.92)14 (25.45)
    Satellite lesions, no. (%)0.69a
        Yes13 (20.63)13 (23.64)
        No50 (79.37)42 (76.36)
    Adenopathy associated, no. (%)0.3d
        Yes3 (4.76)6 (10.91)
        No60 (95.24)49 (89.09)
    Maximum diameter of largest lesion (mm), median (IQR)30 (23.8–40)32.5 (26–46)0.48b
    Area of largest lesion (mm2), median (IQR)548.99 (412.33–1,193.80)659.73 (351.85–1,481.26)0.72b
Leishmania strains, no. (%)0.51c
    L. (V.) panamensis20 (66.67)22 (73.33)
    L. (V.) braziliensis1 (3.33)2 (6.67)
    L. mexicana01 (3.33)
    Not isolated9 (30.00)5 (16.67)
  • a χ2 test.

  • b Mann-Whitney U test.

  • c t test.

  • d Fisher exact test.