Table 1.

Binding of [14C]mersacidin to M. luteus ATCC 4698 after preincubationa with inhibitors of cell wall biosynthesis

AntibioticConcnbAntibiotic/ [14C]mersacidincBinding (%)d
Mersacidin
 Unlabeled20217
 Unlabeled100107
Actagardine2013.54
Vancomycin202.498
831085
Moenomycin20115125
Penicillin G2021.6100
Ramoplanin 200.320
667102
Bacitracin203.86
  • a 5 min.

  • b Multiple of the MIC.

  • c Molar ratio.

  • d Relative to the control culture without preincubation.