Table 1.

MICs, RFLP analysis results, and QRDR sequencing data for MS strains

StrainMICa(μg/ml)RFLP analysisbgyrA sequencing datac
grlAgyrA
16.379/80NoneWild type
212.579/80NoneWild type
312.579/80NoneWild type
412.579/80NoneWild type
52579/80NoneWild type
62579/80NoneWild type
712.584NoneTTT110→TTC; silent
82584NoneTCA112→TCG; silent
92584NoneWild type
105079/8083/84
115079/8083/84
12>10079/8083/84
13>10079/8083/84
  • a MIC of norfloxacin.

  • b Codon(s) in which a mutation(s) resulting in loss or acquisition of recognition sites was found.

  • c This sequencing was done only for strains lacking RFLP-detected gyrA mutations.