Table 2.

Mutations in the gyrA gene in 344S. aureus strains

Codon(s)Mutation(s)No. of isolatesMethod(s)
73Asp→Gly (GAC→GGC)1SSCP, sequencing
84Ser→Leu (TCA→TTA)121SSCP
86Ile [silent] (ATT→ATC)8SSCP
88Glu→Lys (GAA→AAA)36SSCP
84 + 73Ser→Leu (TCA→TTA), Asp→Gly (GAC→GGC)3SSCP, sequencing
84 + 85Ser→Leu (TCA→TTA), Ser→Pro (TCT→CCT)6SSCP, sequencing
84 + 86Ser→Leu (TCA→TTA), Ile [silent] (ATT→ATC)9SSCP
84 + 88Ser→Leu (TCA→TTA), Glu→Lys (GAA→AAA)4SSCP, sequencing
None156SSCP