Table 1.

Mutations in the grlA gene in 344S. aureus strains

Codon(s)Mutation(s)No. of isolatesMethod(s)
77His [silent] (CAT→CAC)7SSCP, sequencing
80Ser→Phe (TCC→TTC)94SSCP
Ser→Tyr (TCC→TAC)43RFLP, sequencing
84Glu→Lys (GAA→AAA)5RFLP
100Ile [silent] (ATA→ATT)4SSCP, sequencing
80 + 81Ser→Phe (TCC→TTC), Ser→Pro (TCA→CCA)1SSCP, sequencing
80 + 84Ser→Phe (TCC→TTC), Glu→Lys (GAA→AAA)8SSCP, sequencing
Ser→Tyr (TCC→TAC), Glu→Lys (GAA→AAA)41RFLP, sequencing
81 + 84Ser→Pro (TCA→CCA), Glu→Lys (GAA→AAA)1SSCP, sequencing
None140SSCP