Table 5.

Fungicidal activities of triazoles and AMB against filamentous fungi other than Aspergillus spp.

OrganismDrugMIC (μg/ml)MFC99(μg/ml)MFC95 (μg/ml)MFC90 (μg/ml)
Trichophyton rubrum A26761 BMS0.13>16>16>16
FLU2>128>128>128
ITR0.25>16>16>16
AMB0.50.25
Trichophyton mentagrophytes A27979 BMS0.03>2>2>2
FLU2>128>128>128
ITR0.06>2>2>2
Microsporum gypseum A26835 BMS0.13>2>2>2
FLU128>128>128>128
ITR0.5>2>2>2
Epidermophyton floccosum A26765 BMS0.03>211
FLU4>128>128>128
ITR0.060.50.50.5
Curvulariasp. strain SC8156BMS21688
FLU8>128>128>128
ITR0.5>1644
AMB0.5321616
Curvularia sp. strain SC2475BMS1>16>16>16
FLU3264
ITR0.25844
AMB0.13411
Cladosporium carrionii ATCC 22864BMS0.13>16>16>16
FLU8>128>128>128
ITR0.13>16>16>16
AMB4>32>324
Fonsecaea pedrosi A26042 BMS0.13>16>16>16
FLU64>128
ITR0.13>32328
AMB4>16>16>16
Phialophora verrucosa ATCC 4806BMS0.06444
FLU32>128
ITR0.060.50.50.5
AMB24
Pseudallescheria boydii A25933 BMS>16>16>16>16
FLU>128>128>128>128
ITR>16>16>16>16
AMB8>32>32>32
Sporothrix schenckii A25976 BMS1>16>16>16
FLU>128>128
ITR0.5>16>16>16
AMB11