Table 3.

Fungicidal activities of triazoles and AMB for yeast strains

OrganismDrugMIC (μg/ml)MFC99 (μg/ml)
Candida albicans A28235 BMS≤0.007>16
ITR0.03>16
FLU0.25>128
AMB0.250.5
Candida albicans A28200 BMS≤0.007>16
ITR0.015>16
FLU0.25>128
AMB0.250.5
Candida tropicalis A26003 BMS0.2516
ITR0.25>16
FLU1>128
AMB0.250.5
Candida krusei A25819 BMS0.0616
ITR0.0616
FLU3264
AMB0.50.5
Candida lusitaniae A25882 BMS≤0.007>16
ITR0.015>16
FLU0.131
AMB11
Candida glabrata A25989 BMS0.12>16
ITR0.25>16
FLU16>128
AMB0.50.5
Cryptococcus neoformans A28201 BMS0.0154 (MIC95 = 0.25)
ITR≤0.0074 (MIC95 = 0.25)
FLU1>128 (MIC95 > 128)
AMB0.250.5 
Cryptococcus neoformans A25838 BMS0.060.5 
ITR0.060.25
FLU1>128 (MFC95 > 128)
AMB0.130.25
Cryptococcus neoformans A26037 BMS0.0080.06 (MFC95 = 0.06)
ITR0.008>2 (MFC95 > 2)
CryptococcusSC15116BMS0.0021 (MFC95 = 1)
ITR0.0021 (MFC95 = 0.5)