Table 3.

Fungicidal activities of triazoles and AMB for yeast strains

OrganismDrugMIC (μg/ml)MFC99 (μg/ml)
Candida albicansA28235BMS≤0.007>16
ITR0.03>16
FLU0.25>128
AMB0.250.5
Candida albicansA28200BMS≤0.007>16
ITR0.015>16
FLU0.25>128
AMB0.250.5
Candida tropicalisA26003BMS0.2516
ITR0.25>16
FLU1>128
AMB0.250.5
Candida kruseiA25819BMS0.0616
ITR0.0616
FLU3264
AMB0.50.5
Candida lusitaniaeA25882BMS≤0.007>16
ITR0.015>16
FLU0.131
AMB11
Candida glabrataA25989BMS0.12>16
ITR0.25>16
FLU16>128
AMB0.50.5
Cryptococcus neoformansA28201BMS0.0154 (MIC95 = 0.25)
ITR≤0.0074 (MIC95 = 0.25)
FLU1>128 (MIC95 > 128)
AMB0.250.5 
Cryptococcus neoformansA25838BMS0.060.5 
ITR0.060.25
FLU1>128 (MFC95 > 128)
AMB0.130.25
Cryptococcus neoformansA26037BMS0.0080.06 (MFC95 = 0.06)
ITR0.008>2 (MFC95 > 2)
CryptococcusSC15116BMS0.0021 (MFC95 = 1)
ITR0.0021 (MFC95 = 0.5)